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1

Synthesis and structure-activity relationships of 3,5-disubstituted-pyrrolo[2,3- b ]pyridines as inhibitors of adaptor associated kinase 1 (AAK1) with antiviral activity

Verdonck, Sven, Pu, Szu-Yuan, Sorrell, Fiona J., Elkins, Jonathan M, Froeyen, Matheus, Gao, Ling-Jie, Prugar, Laura I., Dorosky, Danielle E., Brannan, Jennifer M., Barouch-Bentov, Rina, Knapp, Stefan,

Journal:

Journal of Medicinal Chemistry

Year:

2019

Language:

english

File:

PDF, 1.24 MB

english, 2019

2

Characterization of an efficient dengue virus replicon for development of assays of discovery of small molecules against dengue virus

Yang, Chi-Chen, Tsai, Ming-Han, Hu, Han-Shu, Pu, Szu-Yuan, Wu, Ren-Huang, Wu, Szu-Huei, Lin, Hui-Mei, Song, Jen-Shin, Chao, Yu-Sheng, Yueh, Andrew

Journal:

Antiviral Research

Year:

2013

Language:

english

File:

PDF, 1.23 MB

english, 2013

3

2565. A Novel Prognostic Gene Set for the Prediction of Severe Dengue

Robinson, Makeda L, Sweeney, Timothy E, Barouch-Bentov, Rina, Sahoo, Malaya K, Sanz, Ana Maria, Pu, Szu-Yuan, Ortiz, Eliana, Albornoz, Luis, Suarez, Fernando Rosso, Montoya, Jose G, Pinsky, Benjamin,

Journal:

Open Forum Infectious Diseases

Year:

2018

File:

PDF, 100 KB

2018

4

Single-cell transcriptional dynamics of flavivirus infection

Zanini, Fabio, Pu, Szu-Yuan, Bekerman, Elena, Einav, Shirit, Quake, Stephen R

Journal:

Year:

2018

Language:

english

File:

PDF, 3.97 MB

english, 2018

5

Structure-activity relationship study of the pyridine moiety of isothiazolo[4,3-b]pyridines as antiviral agents targeting cyclin G-associated kinase

Martinez-Gualda, Belén, Pu, Szu-Yuan, Froeyen, Mathy, Herdewijn, Piet, Einav, Shirit, De Jonghe, Steven

Journal:

Bioorganic & Medicinal Chemistry

Year:

2019

Language:

english

File:

PDF, 1.66 MB

english, 2019

6

Optimization of isothiazolo[4,3-b]pyridine-based inhibitors of cyclin G associated kinase (GAK) with broad-spectrum antiviral activity

Pu, Szu-Yuan, Wouters, Randy, Schor, Stanford, Rozenski, Jef, Barouch-Bentov, Rina, Prugar, Laura I, Obrien, Cecilia M, Brannan, Jennifer M, Dye, John M., Herdewijn, Piet, De Jonghe, Steven, Einav, Sh

Journal:

Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 1.24 MB

english, 2018

7

DNA methylation and genome rearrangement characteristics of phase change in cultured shoots of Sequoia sempervirens

Li-Chun Huang, Lin-June Hsiao, Szu-Yuan Pu, Ching-I Kuo, Bau-Lian Huang, Tsung-Che Tseng, Hao-Jen Huang, Yu-Ting Chen

Journal:

Physiologia Plantarum

Year:

2012

Language:

english

File:

PDF, 800 KB

english, 2012

8

Potent antiviral activity of novel multi-substituted 4-anilinoquin(az)olines

Saul, Sirle, Pu, Szu-Yuan, Zuercher, William J., Einav, Shirit, Asquith, Christopher R.M.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2020

File:

PDF, 588 KB

2020

9

Cyclin G-associated kinase (GAK) affinity and antiviral activity studies of a series of 3-C-substituted isothiazolo[4,3-b]pyridines

Wouters, Randy, Pu, Szu-Yuan, Froeyen, Mathy, Lescrinier, Eveline, Einav, Shirit, Herdewijn, Piet, De Jonghe, Steven

Journal:

European Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 911 KB

english, 2018

10

Feasibility and biological rationale of repurposing sunitinib and erlotinib for dengue treatment

Pu, Szu-Yuan, Xiao, Fei, Schor, Stanford, Bekerman, Elena, Zanini, Fabio, Barouch-Bentov, Rina, Nagamine, Claude M., Einav, Shirit

Journal:

Antiviral Research

Year:

2018

Language:

english

File:

PDF, 1.63 MB

english, 2018

11

Anticancer kinase inhibitors impair intracellular viral trafficking and exert broad-spectrum antiviral effects

Bekerman, Elena, Neveu, Gregory, Shulla, Ana, Brannan, Jennifer, Pu, Szu-Yuan, Wang, Stanley, Xiao, Fei, Barouch-Bentov, Rina, Bakken, Russell R., Mateo, Roberto, Govero, Jennifer, Nagamine, Claude M.

Journal:

The Journal of clinical investigation

Year:

2017

Language:

english

File:

PDF, 1.70 MB

english, 2017

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